Antioxidant Activity of 3-[N-(Acylhydrazono)ethyl]-4-hydroxy-coumarins

@inproceedings{Kotali2016AntioxidantAO,
  title={Antioxidant Activity of 3-[N-(Acylhydrazono)ethyl]-4-hydroxy-coumarins},
  author={Antigoni Kotali and Despina A. Nasiopoulou and Constantinos A. Tsoleridis and Philip A Harris and Christos A. Kontogiorgis and Dimitra Hadjipavlou-Litina},
  booktitle={Molecules},
  year={2016}
}
A series of 3-acylhydrazono-4-hydroxycoumarins were synthesized via condensation of 3-acetyl-4-hydroxycoumarin with appropriate hydrazides. The structures of the newly-synthesized compounds were characterized by spectral and elememental analysis or HRMS measurements. Their antioxidant properties were evaluated by using scavenging effects on 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical as well as inhibition of lipid peroxidation. Moreover, their ability to inhibit in vitro soybean lipoxygenase… CONTINUE READING

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