Antioxidant Actions of Dried Flower Extracts of Hibiscus sabdariffa L. On Sodium Arsenite - Induced Oxidative Stress in Rats

@article{IFUsoh2005AntioxidantAO,
  title={Antioxidant Actions of Dried Flower Extracts of Hibiscus sabdariffa L. On Sodium Arsenite - Induced Oxidative Stress in Rats},
  author={. I.F.Usoh and . E.J.Akpan and . E.O.Etim and Ebenezer O Farombi},
  journal={Pakistan Journal of Nutrition},
  year={2005},
  volume={4},
  pages={135-141}
}
2 Abstract: The antioxidant actions of 80% ethanolic extract of dried flowers of Hibiscus sabdariffa L. (HSE) on lipid peroxidation (LPO), reduced glutathione (GSH), glutathione-s-transferase (GST), catalase (CAT), superoxide dismutase (SOD) and vitamin C (VITC), were examined using a model of sodium arsenite (SA) - induced oxidative stress in rats. The oral administration of the extracts (200 and 300mg/kg body weight) significantly (P<0.05) decreased by 37% SA - induced malondialdehyde (MDA… Expand

Tables from this paper

Antioxidant and Hepatoprotective Effects of Dried Flower Extracts of Hibiscus sabdariffa L. on Rats Treated with Carbon Tetrachloride
The hypolipidemic, antioxidative and hepatoprotective activities of 200 and 300mg/kg body weight ethanolic extract of dried flower of Hibiscus sabdariffa L. (HSE) were assessed in rats treated withExpand
Effects of Ethanolic Root Bark Extract of Chrysophyllum albidum on Serum Superoxide Dismutase, Catalase and Malondialdehyde in Rat
Purpose: The ethanolic root bark of Chrysophyllum albidum were evaluated for their effect on antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT) and lipid peroxidationExpand
Alteration in Antioxidant Enzyme Activities by Nickel-Induced Hepatotoxicity in Wistar Rats: Ameliorating Effect of the Aqueous Extract of Myristica fragrans (nutmeg)
The ameliorating effect of Myristica fragrans (nutmeg) on lipid peroxidation (LOP), reduced glutathione (GSH), glutathione-s-transferaes (GST), glutathione peroxidase (GPx), Catalase (CAT),Expand
Extracts of Ocimum gratissimum Leaves Inhibits Fe2+ and Sodium Nitroprusside Induced Oxidative Stress in Rat Liver
TLDR
Fe II and sodium nitroprusside induced oxidative stress could be managed by dietary intake of Ocimum gratissimum leaves. Expand
ANTIOXIDATIVE PROPERTIES OF ETHYL ACETATE FRACTION OF UNRIPE PULP OF CARICA PAPAYA IN MICE
Unripe Carica papaya fruits were extracted with methanol in Soxhlet apparatus and later with a liquid-liquid extraction with the aim of identifying and quantifying secondary metabolite fraction ofExpand
Protective role of tannin-rich fraction of Camellia sinensis in tissue arsenic burden in Sprague Dawley rats
TLDR
Results indicate that the tannin-rich green tea could have improved the defense mechanism against arsenic-induced oxidative stress and reduced the tissue arsenic burden. Expand
The Effect of Ginger Extract ( Zingiber officinale Roscoe ) on antioxidant enzymes and free radical in rabbits
Ginger rhizome has a long history of use in traditional systems of medicine has been found to possess antioxidant effect that can control the generation of free radicals. Free radical level has beenExpand
Influence of Polyphenolic Contents on the Antioxidant Properties of Hibiscus sabdariffa Extract (HSE), Aged Garlic Extract (AGE) and Garlic Tablet (GT) in Vitro
This study compared the antioxidant properties of Hibiscus sabdariffa extract (HSE), commercial aged garlic extract (AGE, Kyolic) and garlic tablet (GT). The results indicate that HSE, AGE and GTExpand
The protective effect of aqueous extracts of roselle (Hibiscus sabdariffa L. UKMR-2) against red blood cell membrane oxidative stress in rats with streptozotocin-induced diabetes
TLDR
The present study demonstrates that aqueous extracts of roselle possess a protective effect against red blood cell membrane oxidative stress in rats with streptozotocin-induced diabetes, and suggests that roselsle can be used as a natural antioxidative supplement in the prevention of oxidative damage in diabetic patients. Expand
In vitro and In vivo Evaluation of Antioxidant Properties of Moringa Oleifera Ethanolic Leaves Extract and Effect on Serum Lipid Indices in Rat
TLDR
The extract had appreciable phenol content and exhibited in vitro antioxidant properties and had modulating effects on enzymatic antioxidants, showed lipid-lowering ability and caused changes in types of lipoproteins found in serum. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 43 REFERENCES
Protective effects of dried flower extracts of Hibiscus sabdariffa L. against oxidative stress in rat primary hepatocytes.
TLDR
The results indicated that the dried flower extracts of H. sabdariffa L. protect rat hepatocytes from t-BHP-induced cytotoxicity and genotoxicity by different mechanisms. Expand
Modulatory influence of Adhatoda vesica (Justicia adhatoda) leaf extract on the enzymes of xenobiotic metabolism, antioxidant status and lipid peroxidation in mice
TLDR
Findings are suggestive of the possible chemopreventive role played by Adhatoda leaf extract in the potential of the machinery associated with the detoxification of xenobiotic compounds. Expand
Antioxidant properties of hard winter wheat extracts
Abstract Extracts from three winter wheat varieties (‘Trego’, ‘Akron’ and ‘Platte’) were evaluated and compared to α-tocopherol for their inhibitory effects on lipid peroxidation in fish oils byExpand
Antioxidant Activities of Caffeic Acid and Its Related Hydroxycinnamic Acid Compounds
Hydroxycinnamic acid compounds are an important source of antioxidants due to their ubiquitous occurrence in the plant kingdom and their characteristic activities. In this study, we compared theExpand
Antioxidant activity and total phenolics in selected cereal grains and their different morphological fractions.
TLDR
Among the water extracts, only the one prepared from buckwheat exhibited antioxidant activity at the concentration analyzed, and the antioxidant activity was observed in extract prepared from separated parts of buckWheat and barley. Expand
Flavonoid constituents of Chorizanthe diffusa with potential cancer chemopreventive activity.
An ethyl acetate-soluble extract of Chorizanthe diffusa was found to exhibit significant antioxidant activity, as judged by scavenging stable 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radicals andExpand
A novel antioxidant flavonoid (IdB 1031) affecting molecular mechanisms of cellular activation.
TLDR
The effects, as a whole, depict this compound as a drug candidate for diseases in which peroxidative damage is associated with the induction of inflammatory responses and specifically with activation of a respiratory burst of leucocytes. Expand
Use of a Free Radical Method to Evaluate Antioxidant Activity
The antiradical activities of various antioxidants were determined using the free radical, 2,2-Diphenyl-1-picrylhydrazyl (DPPH*). In its radical form. DPPH* has an absorption band at 515 nm whichExpand
Glutathione: toxicological implications.
  • D. J. Reed
  • Chemistry, Medicine
  • Annual review of pharmacology and toxicology
  • 1990
TLDR
The role of mitochondrial glutathione in cellular response to toxic exposures that include loss of the homeostases of Ca2+ and protein thiols is described. Expand
Antioxidants in human health and disease.
  • B. Halliwell
  • Chemistry, Medicine
  • Annual review of nutrition
  • 1996
TLDR
Experimental approaches to the optimization of antioxidant nutrient intake are proposed, and interest is also growing in the role of plant phenolics, especially flavonoids. Expand
...
1
2
3
4
5
...