Antiobesity effect ofGynostemma pentaphyllumextract (actiponin): A randomized, double-blind, placebo-controlled trial: Antiobesity Effect of Heat-ProcessedG. pentaphyllumExtract

  title={Antiobesity effect ofGynostemma pentaphyllumextract (actiponin): A randomized, double-blind, placebo-controlled trial: Antiobesity Effect of Heat-ProcessedG. pentaphyllumExtract},
  author={Soo-Hyun Park and T.-L. Huh and Sun Young Kim and Mi-Ra Oh and Pichiah Balasubramanian Tirupathi Pichiah and Soo-Wan Chae and Youn-Soo Cha},
Genome-Wide Identification of R2R3-MYB Transcription Factors: Discovery of a “Dual-Function” Regulator of Gypenoside and Flavonol Biosynthesis in Gynostemma pentaphyllum
A novel transcriptional regulatory mechanism is highlighted that suggests that GpMYB81 acts as a “dual-function” regulator of gypenoside and flavonol biosynthesis in G. pentaphyllum.
Causes and solutions to "globesity": The new fa(s)t alarming global epidemic.
Hypocholesterolemic effect of quercetin-rich onion peel extract in C57BL/6J mice fed with high cholesterol diet
It is suggested that OP promoted lowering of serum and hepatic cholesterol in mice primarily via fecal excretion and hypocholesterolemic effects.


5‐Aminoimidazole‐4‐Carboxamide Ribonucleoside
AICAR provides direct evidence that the inhibition by AMPK of activation of hormone-sensitive lipase by cyclic-AMP-dependent protein kinase also operates in intact cells, and should be a useful tool for identifying new target pathways and processes regulated by theprotein kinase cascade.
Inhibition of fatty acid and cholesterol synthesis by stimulation of AMP‐activated protein kinase
Findings open new perspectives for the simultaneous control of triglyceride and cholesterol synthesis by pharmacological stimulators of AMP‐activated protein kinase.
Gypenosides induced G0/G1 arrest via inhibition of cyclin E and induction of apoptosis via activation of caspases-3 and -9 in human lung cancer A-549 cells.
Gyp appears to exert its anticancer properties by inducing GO/GI-phase arrest and apoptosis via activation of caspase-3 in human lung A549 cancer cells.
Sports anemia: A review of the literature
In general, sports anemia has been found to be a self-limiting condition and usually does not require treatment.
Effects of Metformin and Weight Loss on Serum Alanine Aminotransferase Activity in the Diabetes Prevention Program
Over 3 years of follow-up in persons at high risk for development of diabetes, serum ALT was consistently lower in those treated with metformin compared with placebo, indicating that the effects of metform in therapy on ALT is via its effects on weight.
First clinical studies with orlistat: a short review.
Orlistat, a lipase inhibitor, in a dose of 50 mg three times a day leads to a significant increase in weight loss compared to placebo in moderately obese people and is tolerated very well, although a higher occurrence of gastrointestinal side effects is seen.
Potential hypoglycemic effect of an ethanol extract of Gynostemma pentaphyllum in C57BL/KsJ-db/db mice.
The results suggest that the supplementation of high-dose GPE (0.01%) in the diet lowers the blood glucose level by altering the hepatic glucose metabolic enzyme activities.
Diurnal rhythm of phosphorylation of rat liver acetyl-CoA carboxylase by the AMP-activated protein kinase, demonstrated using freeze-clamping. Effects of high fat diets.
The results provide a rational explanation for the post mortem phosphorylation events, and re-emphasize the point that rapid cooling of cells and tissues is essential when measuring the expressed activity of acetyl-CoA carboxylase (as well as 3-hydroxy-3-methylglutaryl- CoA reductase).