Antiobesity carbonic anhydrase inhibitors.

@article{Simone2007AntiobesityCA,
  title={Antiobesity carbonic anhydrase inhibitors.},
  author={Giuseppina De Simone and Claudiu T. Supuran},
  journal={Current topics in medicinal chemistry},
  year={2007},
  volume={7 9},
  pages={
          879-84
        }
}
Few pharmacological approaches for the treatment of obesity exist at this time, and most of them are unsatisfactory, whereas this disease is widespread both in the developed and developing world. Novel effective approaches are needed for the development of antiobesity agents possessing different mechanisms of action. A possible new approach for the treatment and prophylaxis of obesity is based on the inhibition of carbonic anhydrases (CAs, EC 4.2.1.1), enzymes involved in several steps of de… CONTINUE READING
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