Antinuclear antibodies as ancillary markers in primary biliary cirrhosis

@article{Granito2012AntinuclearAA,
  title={Antinuclear antibodies as ancillary markers in primary biliary cirrhosis},
  author={Alessandro Granito and Paolo Muratori and Chiara Quarneti and Georgios Pappas and Ronny Cicola and Luigi Muratori},
  journal={Expert Review of Molecular Diagnostics},
  year={2012},
  volume={12},
  pages={65 - 74}
}
Antimitochondrial antibodies are the serological hallmark of primary biliary cirrhosis (PBC). Besides antimitochondrial antibodies, the autoantibody profile of PBC includes antinuclear antibodies (ANA) which are detectable by indirect immunofluorescence in up to 50% of PBC patients. Two immunofluorescence patterns are considered ‘PBC-specific’: the multiple nuclear dots and rim-like/membranous patterns. The target antigens of the multiple nuclear dots pattern have been identified as Sp100 and… 
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Promyelocytic Leukemia Antigen Expression: a Histological Marker for Primary Biliary Cholangitis Diagnosis?
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