Antinociceptive properties in mice of a lectin isolated from the marine alga Amansia multifida Lamouroux.

@article{Neves2007AntinociceptivePI,
  title={Antinociceptive properties in mice of a lectin isolated from the marine alga Amansia multifida Lamouroux.},
  author={S. A. Neves and A. Freitas and B. Sousa and M. A. Rocha and M. Correia and D. A. Sampaio and G. Viana},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  year={2007},
  volume={40 1},
  pages={
          127-34
        }
}
  • S. A. Neves, A. Freitas, +4 authors G. Viana
  • Published 2007
  • Chemistry, Medicine
  • Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
The antinociceptive effects of a lectin (LEC) isolated from the marine alga Amansia multifida were determined in Swiss mice. The LEC (1, 5, and 10 mg/kg) inhibited acetic acid-induced abdominal writhings in a dose-dependent manner after intraperitoneal or oral administration. A partial but significant inhibition of writhings was observed after the combination of LEC (10 mg/kg) with avidin (1 mg/kg), a potent inhibitor of the hemmaglutinant activity of the lectin. However, total writhing… Expand
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