Antinociceptive effects induced through the stimulation of spinal cannabinoid type 2 receptors in chronically inflamed mice.

@article{CurtoReyes2011AntinociceptiveEI,
  title={Antinociceptive effects induced through the stimulation of spinal cannabinoid type 2 receptors in chronically inflamed mice.},
  author={Verdad Curto-Reyes and Tamara Boto and Agust{\'i}n Hidalgo and Luis Armando Men{\'e}ndez and Ana Baamonde},
  journal={European journal of pharmacology},
  year={2011},
  volume={668 1-2},
  pages={184-9}
}
The stimulation of spinal cannabinoid type 2 (CB(2)) receptors is a suitable strategy for the alleviation of experimental pain symptoms. Several reports have described the up-regulation of spinal cannabinoid CB(2) receptors in neuropathic settings together with the analgesic effects derived from their activation. Besides, we have recently reported in two murine bone cancer models that the intrathecal administration of cannabinoid CB(2) receptor agonists completely abolishes hyperalgesia and… CONTINUE READING
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Identification and functional characterization of brainstem cannabinoid CB2 receptors

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