Antinociceptive effect of calcitonin gene-related peptide in the central nucleus of amygdala: activating opioid receptors through amygdala-periaqueductal gray pathway.

@article{Xu2003AntinociceptiveEO,
  title={Antinociceptive effect of calcitonin gene-related peptide in the central nucleus of amygdala: activating opioid receptors through amygdala-periaqueductal gray pathway.},
  author={Wencong Xu and Thomas Lundeberg and Y. T. Wang and Y-q Li and L Yu},
  journal={Neuroscience},
  year={2003},
  volume={118 4},
  pages={1015-22}
}
The central nucleus of amygdala (CeA) plays an important role in pain regulation. Calcitonin gene-related peptide (CGRP)-like immunoreactive fibers and CGRP receptors are distributed densely in CeA. The present study was performed to elucidate the role of CGRP in nociceptive regulation in the CeA of rats. Intra-CeA injection of CGRP induced dose-dependent increases in the hind-paw withdrawal latency tested by hotplate test and Randall Selitto Test, indicating an antinociceptive effect of CGRP… CONTINUE READING
16 Citations
41 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 41 references

The rat brain in stereotaxic coordinates, 2nd edition

  • G Paxinos, C Watson
  • 1986
Highly Influential
3 Excerpts

Similar Papers

Loading similar papers…