Antinociceptive effect of botulinum toxin type a in rat model of carrageenan and capsaicin induced pain.

@article{BachRojecky2005AntinociceptiveEO,
  title={Antinociceptive effect of botulinum toxin type a in rat model of carrageenan and capsaicin induced pain.},
  author={Lidija Bach-Rojecky and Zdravko Lackovi{\'c}},
  journal={Croatian medical journal},
  year={2005},
  volume={46 2},
  pages={201-8}
}
AIM To test antinociceptive properties of botulinum toxin type A (BTX-A) in rats with carrageenan- and capsaicin-induced pain and inflammation. METHODS Pain was provoked with carrageenan (1%) or capsaicin (0.1%) injection into the plantar surface of the rat paw-pad. The effect of BTX-A 5 U/kg on carrageenan- and capsaicin-induced mechanical and thermal hypersensitivity, as well as the size of carrageenan-induced paw edema were tested 24 hours and 6 days following the toxin injection into the… CONTINUE READING