Antinociceptive effect of a novel tosylpyrazole compound in mice.

  title={Antinociceptive effect of a novel tosylpyrazole compound in mice.},
  author={Sara Marchesan Oliveira and Camila de Campos Velho Gewehr and Gerusa Duarte Dalmolin and Cl{\'e}ber Andr{\'e} Cechinel and Alexandre Pereira Wentz and Rog{\'e}rio V. Lourega and Ronan C Sehnem and Nilo Zanatta and Marcos A P Martins and Maribel A Rubin and Helio G Bonacorso and Juliano Ferreira},
  journal={Basic & clinical pharmacology & toxicology},
  volume={104 2},
Pain is the most common complaint in the medical field and the identification of compounds that can effectively treat painful states without induction of side-effects remains a major challenge in biomedical research. The aim of the present study was to investigate the antinociceptive effect of a novel compound, 3-(4-fluorophenyl)-5-trifluoromethyl-1H-1-tosylpyrazole (compound A) in several models of pain in mice and compare with those produced by the known trifluoromethyl-containing pyrazole… CONTINUE READING


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