Antinociceptive and antiinflammatory activities and QSAR studies on 2-substituted-4,5-diphenyl-1H-imidazoles.

Abstract

This paper describes the pharmacological evaluation pertaining to antinociceptive (hot plate and tail flick) and antiinflammatory (based on Carrageenan-induced paw oedema) activities, and QSAR studies on 2-substituted-4,5-diphenyl-1H-imidazoles. Compounds with phenyl substitution with -F, -Cl, -NH(2), -N(CH(3))(2), -OH and -OCH(3) at the p-position showed… (More)

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@article{Puratchikody2007AntinociceptiveAA, title={Antinociceptive and antiinflammatory activities and QSAR studies on 2-substituted-4,5-diphenyl-1H-imidazoles.}, author={Ayarivan Puratchikody and Mukesh Doble}, journal={Bioorganic & medicinal chemistry}, year={2007}, volume={15 2}, pages={1083-90} }