Antinociceptive and antiedematogenic effect of pecan (Carya illinoensis) nut shell extract in mice: a possible beneficial use for a by-product of the nut industry

  title={Antinociceptive and antiedematogenic effect of pecan (Carya illinoensis) nut shell extract in mice: a possible beneficial use for a by-product of the nut industry},
  author={Gabriela Trevisan and Mateus Rossato and Carin Hoffmeister and Liz Girardi M{\"u}ller and Camila Simonetti Pase and Marina Machado C{\'o}rdova and Fernanda Rosa and Raquel Tonello and Bruna S. Hausen and Aline Augusti Boligon and Rafael Noal Moresco and Margareth Linde Athayde and Marilise E Burguer and Adair Roberto Soares Santos and Juliano Ferreira},
  journal={Journal of Basic and Clinical Physiology and Pharmacology},
  pages={401 - 410}
Abstract Background: Interest in pecan (Carya illinoensis) nut shells, a by-product of the nut industry, has increased due to its anti-inflammatory and antioxidant activities. The goal of this study was to evaluate the antinociceptive and antiedematogenic activity and the mechanisms of the pecan shell aqueous extract (AE). Methods: First, we performed fingerprinting of C. illinoensis AE. The antinociceptive and antiedematogenic effects of AE intragastric (i.g.) administration in mice (male… 

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