Antinociceptive activity of methanolic extracts of St. John's Wort (Hypericum perforatum) preparation.

Abstract

The analgesic effect of St. John's Wort plant preparation was evaluated using chemically induced pain models in adult albino mice. The intraperitoneal (i.p.) administration of 30-100 mg/kg of the preparation produced significant analgesic effect (75%) in acetic acid induced writhing and formalin licking tests. Based on its inhibitory effects on acetic acid… (More)

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