Antinociceptive activity of lectins from Diocleinae seeds on acetic acid-induced writhing test in mice.

Abstract

Diocleinae lectins administered per oral route in mice inhibited the abdominal constrictions induced by acetic acid. The percentage of the lectins antinociception varied from 61% for Canavalia grandiflora (ConGf) to 20% for Dioclea violacea. ConGf inhibited contortions at all doses tested but not in a dose-dependent manner, involving carbohydrate recognition.

Cite this paper

@article{Holanda2009AntinociceptiveAO, title={Antinociceptive activity of lectins from Diocleinae seeds on acetic acid-induced writhing test in mice.}, author={Fernanda R Holanda and Andrelina N Coelho-de-Sousa and Ana Maria Sampaio Assreuy and Jos{\'e} Henrique Leal-Cardoso and Alana de Freitas Pires and Kyria Santiago do Nascimento and C{\'i}cero Silvano Teixeira and B. S. Cavada and Cl{\'a}udia Ferreira Santos}, journal={Protein and peptide letters}, year={2009}, volume={16 9}, pages={1088-92} }