Antinociceptive Synergy, Additivity, and Subadditivity with Combinations of Oral Glucosamine Plus Nonopioid Analgesics in Mice

@article{Tallarida2003AntinociceptiveSA,
  title={Antinociceptive Synergy, Additivity, and Subadditivity with Combinations of Oral Glucosamine Plus Nonopioid Analgesics in Mice},
  author={R. Tallarida and A. Cowan and R. Raffa},
  journal={Journal of Pharmacology and Experimental Therapeutics},
  year={2003},
  volume={307},
  pages={699 - 704}
}
Glucosamine (2-amino-2-deoxy-d-glucose) and glucosamine-containing products have been reported to have efficacy in the treatment of various musculoskeletal disorders. Glucosamine's efficacy, including reduction of pain, is attributed to disease-modifying properties, specifically to cartilage-rebuilding associated with modulation of interleukin-1-induced activation of chondrocytes and to inhibition of proinflammatory effects of the nuclear factor-κB pathway. However, glucosamine has not been… Expand
Synergistic Interaction between the Two Mechanisms of Action of Tapentadol in Analgesia
[An antinociceptive effect of chondroprotectors: a myth or a reality?].
Acetaminophen (Paracetamol) Oral Absorption and Clinical Influences
An isobolographic analysis of the anti-nociceptive effect of geraniin in combination with morphine or diclofenac
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 34 REFERENCES
Complementary and synergistic antinociceptive interaction between the enantiomers of tramadol.
Glucosamine Sulfate for Osteoarthritis
Discovery of "self-synergistic" spinal/supraspinal antinociception produced by acetaminophen (paracetamol).
Effect of glucosamine hydrochloride in the treatment of pain of osteoarthritis of the knee.
Conservative management of spinal osteoarthritis with glucosamine sulfate and chiropractic treatment.
  • M. Gottlieb
  • Medicine
  • Journal of manipulative and physiological therapeutics
  • 1997
Response surface analysis of synergism between morphine and clonidine.
Agonist and antagonist interactions of opioids on acetic acid-induced abdominal stretching in mice.
Statistical analysis of drug-drug and site-site interactions with isobolograms.
...
1
2
3
4
...