Antinociceptive Effects of the Aqueous Extract of Brugmansia suaveolens Flowers in Mice

@article{Parker2007AntinociceptiveEO,
  title={Antinociceptive Effects of the Aqueous Extract of Brugmansia suaveolens Flowers in Mice},
  author={Alexander Garcia Parker and Gianni Goulart Peraza and Jana{\'i}na Sena and Eli Sinnott Silva and Maria C. F. Soares and Marta Regina Cezar Vaz and Eliana Badiale Furlong and Ana Luiza Muccillo-Baisch},
  journal={Biological Research For Nursing},
  year={2007},
  volume={8},
  pages={234 - 239}
}
The infusion of Brugmansia suaveolens, popularly known as trombeteira or cartucheira, has been used to treat pain in Brazil. The present study was conducted to test for its antinociceptive effects using the abdominal-writhing, formalin, tail-flick, and hot-plate tests in mice. The aqueous extract from B. suaveolens flowers administered intraperitoneally at doses of 100 and 300 mg/kg body weight significantly inhibited acetic acid-induced abdominal constrictions. An increase in hot-plate latency… 

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