Antinociceptive Activity of Methanol Extract of Muntingia calabura Leaves and the Mechanisms of Action Involved

@inproceedings{Sani2012AntinociceptiveAO,
  title={Antinociceptive Activity of Methanol Extract of Muntingia calabura Leaves and the Mechanisms of Action Involved},
  author={M. H. Mohd. Sani and Zainul Amirudin Zakaria and Tavamani Balan and Lay Kek Teh and Mohd. Salleh},
  booktitle={Evidence-based complementary and alternative medicine : eCAM},
  year={2012}
}
Muntingia calabura L. (family Elaeocarpaceae) has been traditionally used to relieve various pain-related ailments. The present study aimed to determine the antinociceptive activity of methanol extract of M. calabura leaves (MEMC) and to elucidate the possible mechanism of antinociception involved. The in vivo chemicals (acetic acid-induced abdominal constriction and formalin-, capsaicin-, glutamate-, serotonin-induced paw licking test) and thermal (hot plate test) models of nociception were… CONTINUE READING
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