Antinociceptive, genotoxic and histopathological study of Heliopsis longipes S.F. Blake in mice.

@article{CarioCorts2010AntinociceptiveGA,
  title={Antinociceptive, genotoxic and histopathological study of Heliopsis longipes S.F. Blake in mice.},
  author={Raquel Cari{\~n}o-Cort{\'e}s and Juan A. Gayosso-de-Lucio and Mario I. Ortiz and Manuel S{\'a}nchez-Guti{\'e}rrez and Patricia Garc{\'i}a-Reyna and Virginia Gabriela Cilia-L{\'o}pez and Nury P{\'e}rez-Hern{\'a}ndez and {\'E}rika Marcela Moreno and H{\'e}ctor A. Ponce-Monter},
  journal={Journal of ethnopharmacology},
  year={2010},
  volume={130 2},
  pages={
          216-21
        }
}

Figures from this paper

Antimutagenic properties of affinin isolated from Heliopsis longipes extract

TLDR
Assessment of the potential utilization of the natural product affinin isolated from H. longipes ethanol extract found it to be not mutagenic and possesses antimutagenic activity, which could be important to treat some pain symptoms related to antiradical activity.

Antinociceptive and anti-inflammatory activities of Geranium bellum and its isolated compounds

TLDR
These studies provide evidences that G. bellum shows antinociceptive and anti- inflammatory effects, and gives support to its use in treating pain in Mexican traditional medicine.

Evaluation of antinociceptive activity of acmella uliginosa (sw.) cass. methanolic crude extract in mice

TLDR
It was demonstrated in the present study that MEAU at doses of 3, 10, 30 and 100 mg/kg produced significant dose-dependent inhibition in acetic acid-induced abdominal constriction test, hot plate test, formalin-, capsaicin- and glutamateinduced paw licking test as compared to control, which indicates that the methanolic crude extract of A. uliginosa (Sw.) Cass.

Effects of Heliopsis longipes ethanolic extract on mouse spermatozoa in vitro

TLDR
The results demonstrate the spermicidal activity of HLEE in vitro and suggest that this action is caused by oxidative damage and alterations in the spermatozoal membrane.

Proangiogenic Effect of Affinin and an Ethanolic Extract from Heliopsis longipes Roots: Ex Vivo and In Vivo Evidence

TLDR
This is the first study showing the proangiogenic effect of H. longipes and the ethanolic extract from Heliopsis longipes roots (HLEE), and showed that affinin and the HLEE increased vascular growth in a dose-dependent manner in both bioassays.

Affinin (Spilanthol), Isolated from Heliopsis longipes, Induces Vasodilation via Activation of Gasotransmitters and Prostacyclin Signaling Pathways

TLDR
It is demonstrated, for the first time, that affinin induces vasodilation by mechanisms that involve gasotransmitters, and prostacyclin signaling pathways.

Affinin and hexahydroaffinin: Chemistry and toxicological profile

TLDR
It is suggested that affinin and hexahydroaffinin are not only useful candidates for possible new drugs but also safe compounds.

HPLC Determination of the Alkamide Affinin in Fresh and Dry Roots of Heliopsis longipes (Asteraceae) and HS-SPME-GC-MS-TOF Analysis of Volatile Components

Heliopsis longipes (Asteraceae) is a plant whose roots are commonly used in Mexican cuisine as a substitute for hot pepper. This plant is also used in traditional medicine for its therapeutical

References

SHOWING 1-10 OF 43 REFERENCES

Anti-inflammatory effects of ethanolic extract and alkamides-derived from Heliopsis longipes roots.

Interaction between Heliopsis longipes extract and diclofenac on the thermal hyperalgesia test.

Antigenotoxic, antioxidant and lymphocyte induction effects produced by pteropodine.

TLDR
It is established that pteropodine is an effective antimutagen in the model used, and it is suggested that it deserves further research in the area of cell protective potential and its mechanism of action.

Analgesic activity of affinin, an alkamide from Heliopsis longipes (Compositae).

Phyllanthus maderaspatensis, a dietary supplement for the amelioration of adriamycin-induced toxicity and oxidative stress in mice

TLDR
PME has a protective effect against ADR-induced toxicity, as revealed by the decrease in the concentrations of LDH, CPK, and the frequency of MNPCEs, which are indicative of the antioxidant property of PME.

Black Pepper and its Pungent Principle-Piperine: A Review of Diverse Physiological Effects

  • K. Srinivasan
  • Biology
    Critical reviews in food science and nutrition
  • 2007
TLDR
Piperine has been demonstrated in in vitro studies to protect against oxidative damage by inhibiting or quenching free radicals and reactive oxygen species, and to enhance the bioavailability of a number of therapeutic drugs as well as phytochemicals by this very property.

Fungistatic and bacteriostatic activities of alkamides from Heliopsis longipes roots: affinin and reduced amides.

This work demonstrates the fungistatic and bacteriostatic activities of affinin, the main alkamide of Heliopsis longipes (Gray) Blake (Asteraceae) roots and two alkamides obtained by catalytic

Alkamides: structural relationships, distribution and biological activity.

TLDR
Some olefinic isobutylamides have been shown to possess considerable insecticidal activity and to be effective as molluscicides and cercaricides and thus are of potential use against bilharzia.