Antinociceptive, genotoxic and histopathological study of Heliopsis longipes S.F. Blake in mice.

  title={Antinociceptive, genotoxic and histopathological study of Heliopsis longipes S.F. Blake in mice.},
  author={Raquel Cari{\~n}o-Cort{\'e}s and Juan A Gayosso-De-Lucio and Mario I Ortiz and Manuel S{\'a}nchez-Guti{\'e}rrez and Patricia Garc{\'i}a-Reyna and Virginia Gabriela Cilia-L{\'o}pez and Nury P{\'e}rez-Hern{\'a}ndez and Erika Moreno and H{\'e}ctor A. Ponce-Monter},
  journal={Journal of ethnopharmacology},
  volume={130 2},
ETHNOPHARMACOLOGICAL RELEVANCE H. longipes S.F. Blake (Asteraceae) is a Mexican plant, whose roots are traditionally used as a condiment, as a mouth anesthetic, and as an antiparasitic. Affinin is the alkamide present in higher amounts in the roots of H. longipes. AIM OF THE STUDY To date, there are no published studies regarding the relation between the analgesic properties, in vivo cytotoxicity, and DNA-damaging potential of H. longipes ethanol extract (HLEE). MATERIALS AND METHODS The… CONTINUE READING


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