Antinociceptive, cardiopulmonary, and sedative effects of five intravenous infusion rates of lidocaine in conscious dogs.

@article{MacDougall2009AntinociceptiveCA,
  title={Antinociceptive, cardiopulmonary, and sedative effects of five intravenous infusion rates of lidocaine in conscious dogs.},
  author={Lori M MacDougall and James A Hethey and Alex Livingston and Christopher Clark and Cindy L Shmon and Tanya Duke-Novakovski},
  journal={Veterinary anaesthesia and analgesia},
  year={2009},
  volume={36 5},
  pages={512-22}
}
OBJECTIVE To observe antinociceptive, cardiopulmonary and sedative effects of five different 12-hour lidocaine infusions in conscious dogs, and measure plasma lidocaine concentrations. STUDY DESIGN Two-part randomized, prospective, blinded, cross-over experimental study. ANIMALS Six neutered male, crossbred dogs approximately 1-2 years of age and weighing 29.1 +/- 4.0 kg. METHODS Dogs received lidocaine [2 mg kg(-1), intravenous (i.v.)] or equivalent volume of 0.9% saline followed by… CONTINUE READING
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