Antinociceptive, anti-inflammatory and antipyretic effects of Muntingia calabura aqueous extract in animal models

@article{Zakaria2007AntinociceptiveAA,
  title={Antinociceptive, anti-inflammatory and antipyretic effects of Muntingia calabura aqueous extract in animal models},
  author={Zainul Amiruddin Zakaria and N. A. Mohd Nor Hazalin and Siti Nor Hafizah binti Mohd Zaid and Mohammad J. Abdul Ghani and Memy Hegazy Hassan and Hanan Kumar Gopalan and Mohd. Roslan Sulaiman},
  journal={Journal of Natural Medicines},
  year={2007},
  volume={61},
  pages={443-448}
}
The present study was carried out to elucidate the potential of aqueous extract of Muntingia calabura leaves aqueous extract (MCAE) as antinociceptive, anti-inflammatory and antipyretic agents using the formalin-, carrageenan-induced paw edema- and brewer’s yeast-induced pyrexia tests in rats. The extract was prepared by soaking the dried powdered leaves of M. calabura in distilled water (dH2O) overnight. The supernatant obtained, considered as a stock solution (100% concentration/strength… CONTINUE READING