Antinociception of petroleum ether fraction derived from crude methanol extract of Melastoma malabathricum leaves and its possible mechanisms of action in animal models

@inproceedings{Zakaria2016AntinociceptionOP,
  title={Antinociception of petroleum ether fraction derived from crude methanol extract of Melastoma malabathricum leaves and its possible mechanisms of action in animal models},
  author={Zainul Amirudin Zakaria and E. S. Jaios and Maizatul Hasyima Omar and S. Abd. Rahman and Siti Selina Abdul Hamid and Siew Mooi Ching and Lay Kek Teh and Mohd. Salleh and Sentosa Deny and Muhammad Taher},
  booktitle={BMC complementary and alternative medicine},
  year={2016}
}
BACKGROUND Melastoma malabathricum L. (family Melastomaceae) has been traditionally used as remedies against various ailments including those related to pain. The methanol extract of M. malabathricum leaves has been proven to show antinociceptive activity. Thus, the present study aimed to determine the most effective fraction among the petroleum ether- (PEMM), ethyl acetate- (EAMM) and aqueous- (AQMM) fractions obtained through successive fractionation of crude, dried methanol extract of M… CONTINUE READING
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Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 71 references

In vitro anticoagulant activities of Melastoma malabathricum (L) aqueous leaf extract: a preliminary novel finding

  • C Manicam, JO Abdullah, ER Mohd Tohit, Z Seman, CC Sieo, M. Hamid
  • J Med Plants Res. 2010;4:1464–72
  • 2016
2 Excerpts

Possible mechanisms of antinociception of methanol extract of Melastoma malabathricum leaves

  • ES Jaios, S Abdul Rahman, SM Ching, AK Arifah, MN Desa, ZA. Zakaria
  • Rev Bras Farmacogn
  • 2016
2 Excerpts

Antinociceptive and anti - inflammatory activity of the siaresinolic acid , a triterpene isolated from the leaves of Sabicea grisea Cham . & Schltdl . var . grisea

  • A Beirith, AR Santos, +4 authors RA Yunes
  • J Nat Med
  • 2015

Antinociceptive and anti-inflammatory activity of the siaresinolic acid, a triterpene isolated from the leaves of Sabicea grisea Cham

  • AF de Oliveira AM de Araújo, RP Lyra Lemos, LM Conserva, JN de Souza Ferro, E. Barreto
  • Schltdl. var. grisea. J Nat Med
  • 2015
1 Excerpt

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