Antineutrophil cytoplasmic antibodies in systemic lupus erythematosus. Prevalence, specificities, and clinical significance.

@article{Schnabel1995AntineutrophilCA,
  title={Antineutrophil cytoplasmic antibodies in systemic lupus erythematosus. Prevalence, specificities, and clinical significance.},
  author={Armin Schnabel and Elena Csernok and David Alan Isenberg and Ch. Mrowka and Wolfgang Ludwig Gross},
  journal={Arthritis and rheumatism},
  year={1995},
  volume={38 5},
  pages={633-7}
}
OBJECTIVE To examine the prevalence, subspecificities, and clinical associations of antineutrophil cytoplasmic antibodies (ANCA) in patients with systemic lupus erythematosus (SLE). METHODS One hundred fifty-seven sera from 120 patients with SLE were examined for classic (c) and perinuclear (p) pattern ANCA by indirect immunofluorescence. Antibody subspecificities were determined by enzyme-linked immunosorbent assay (ELISA). Serologic results were correlated with clinical manifestations as… CONTINUE READING

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