Antinephritic effect of prostaglandin E1 on serum sickness nephritis in rats (4). Enhanced clearance of macromolecules by the reticulo-endothelial system with prostaglandin E1.

@article{Nagamatsu1987AntinephriticEO,
  title={Antinephritic effect of prostaglandin E1 on serum sickness nephritis in rats (4). Enhanced clearance of macromolecules by the reticulo-endothelial system with prostaglandin E1.},
  author={Tadashi Nagamatsu and Yoshio Suzuki},
  journal={Japanese journal of pharmacology},
  year={1987},
  volume={44 3},
  pages={369-72}
}
Function of the reticulo-endothelial system (RES) was determined by the carbon clearance technique in rats. Rats in the previous phase of nephritis showed reduced function of the RES with circulating immune complexes compared with normal rats. Prostaglandin E1 (PGE1) at 1.0 mg/kg, s.c., resulted in significant recovery in the impaired RES activity of the… CONTINUE READING