Antimycobacterial and HIV-1 Reverse Transcriptase Activity of Julianaceae and Clusiaceae Plant Species from Mexico

@inproceedings{GmezCansino2015AntimycobacterialAH,
  title={Antimycobacterial and HIV-1 Reverse Transcriptase Activity of Julianaceae and Clusiaceae Plant Species from Mexico},
  author={Roc{\'i}o G{\'o}mez-Cansino and Clara In{\'e}s Espitia-Pinz{\'o}n and Mar{\'i}a Guadalupe Campos-Lara and Silvia Laura Guzm{\'a}n-Guti{\'e}rrez and Erika Segura-Salinas and Gabriela Echeverr{\'i}a-Valencia and Laura Torras-Claveria and Xochitl Marisol Cuevas-Figueroa and Ricardo Reyes-Chilpa},
  booktitle={Evidence-based complementary and alternative medicine : eCAM},
  year={2015}
}
The extracts of 14 Julianaceae and 5 Clusiaceae species growing in Mexico were tested in vitro (50 µg/mL) against Mycobacterium tuberculosis H37Rv and HIV reverse transcriptase (HIV-RT). The Julianaceae bark and leaf extracts inhibited M. tuberculosis (>84.67%) and HIV-RT (<49.89%). The Clusiaceae leaves extracts also inhibited both targets (>58.3% and >67.6%), respectively. The IC50 values for six selected extracts and their cytotoxicity (50 µg/mL) to human macrophages were then determined… CONTINUE READING
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