Corpus ID: 43651565

Antimycobacterial activity of some pyrido-1,2-thiazine derivatives.

@article{Malinka2002AntimycobacterialAO,
  title={Antimycobacterial activity of some pyrido-1,2-thiazine derivatives.},
  author={W. Malinka and A. Redzicka and P. Świątek},
  journal={Acta poloniae pharmaceutica},
  year={2002},
  volume={59 6},
  pages={
          439-42
        }
}
  • W. Malinka, A. Redzicka, P. Świątek
  • Published 2002
  • Chemistry, Medicine
  • Acta poloniae pharmaceutica
    • The 3-benzoylpyrido-1,2-thiazine-1,1-dioxides 1 and the related pyrazolopyrido-1,2-thiazine-5,5-dioxides 2 with a 4-arylpiperazin-1-ylpropyl side chained by the nitrogen atom of the thiazine ring were evaluated in vitro against Myobacterium tuberculosis H37Rv. Some of the tested compounds proved to be potent antimycobacterial agents and for the most active of them (1a,b) minimum inhibitory concentrations (MIC = 3.13 and 6.25 microg/ml, respectively) were determined. The correlation between… CONTINUE READING
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