Antimycobacterial activity of geranylated furocoumarins from Tetradium daniellii.

  title={Antimycobacterial activity of geranylated furocoumarins from Tetradium daniellii.},
  author={M. Adams and Sabine Ettl and O. Kunert and A. Wube and E. Haslinger and F. Bucar and R. Bauer},
  journal={Planta medica},
  volume={72 12},
  • M. Adams, Sabine Ettl, +4 authors R. Bauer
  • Published 2006
  • Chemistry, Medicine
  • Planta medica
  • Seven geranylated furocoumarins were isolated from the fruits of TETRADIUM DANIELLII (Benn.) T.G. Hartley (Rutaceae) and tested for their antimycobacterial activity against MYCOBACTERIUM FORTUITUM, M. SMEGMATIS and M. PHLEI. They were shown to be highly active, with minimal inhibitory concentrations (MICs) ranging from 8 to 64 microg/mL. Xanthotoxin and xanthotoxol, representing furocoumarins lacking the lipophilic geranyl side chain, were tested similarly and were shown to be inactive… CONTINUE READING
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