Antimigraine drugs and cranial arteriovenous shunting in the cat

@article{Spierings1980AntimigraineDA,
  title={Antimigraine drugs and cranial arteriovenous shunting in the cat},
  author={Egilius L. H. Spierings and Pramod R. Saxena},
  journal={Neurology},
  year={1980},
  volume={30},
  pages={696 - 696}
}
  • Egilius L. H. Spierings, Pramod R. Saxena
  • Published 1980
  • Medicine
  • Neurology
  • The effects of three antimigraine drugs—ergotamine, dihydroergotamine, and methysergid—mn the distribution of flow throughout the cephalic circulation of the cat were studied, using microspheres of a suitable size to separate capillary flow from flow through the arteriovenous anastomoses. Ergotamine and dihydroergotamine significantly decreased the fraction of carotid blood flow shunted through the arteriovenous anastomoses, a mode of action that reemphasizes the need for further clinical… CONTINUE READING

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