Antimicrobial synergy between mRNA- and protein-level inhibitors.

@article{Dryselius2005AntimicrobialSB,
  title={Antimicrobial synergy between mRNA- and protein-level inhibitors.},
  author={Rikard Dryselius and Natalia Nekhotiaeva and L. Good},
  journal={The Journal of antimicrobial chemotherapy},
  year={2005},
  volume={56 1},
  pages={97-103}
}
BACKGROUND The few available distinct classes of antimicrobials limits the scope for single and combination drug treatment of resistant infections. OBJECTIVE To evaluate antimicrobial effectiveness from combinations of protein-specific drugs and mRNA-specific antisense inhibitors. METHODS Interactions between conventional antimicrobial drugs and mRNA-specific translation inhibiting antisense peptide nucleic acids were assessed in Escherichia coli and Staphylococcus aureus cultures using… CONTINUE READING
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