Antimicrobial sesquiterpenoids from Laurus nobilis L.

  title={Antimicrobial sesquiterpenoids from Laurus nobilis L.},
  author={N. Fukuyama and C. Ino and Y. Suzuki and N. Kobayashi and H. Hamamoto and K. Sekimizu and Y. Orihara},
  journal={Natural Product Research},
  pages={1295 - 1303}
  • N. Fukuyama, C. Ino, +4 authors Y. Orihara
  • Published 2011
  • Biology, Medicine
  • Natural Product Research
  • Activity-guided fractionations of leaf extracts from Laurus nobilis L. led to the isolation of a known sesquiterpene lactone, deacetyl laurenobiolide (1). Compound 1 showed antimicrobial activity against periopathic pathogens (Actinomyces viscosus, Porphyromonas gingivalis, Prevotella intermedia and Actinobacillus actinomycetemcomitans), opportunistic Gram-positive bacteria (Staphylococcus aureus and Streptococcus pyogenes) and fungi (Candida albicans, Cryptococcus neoformans and Aspergillus… CONTINUE READING
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