Antimicrobial resveratrol tetramers from the stem bark of Vatica oblongifoliassp. oblongifolia.
@article{ZgodaPols2002AntimicrobialRT, title={Antimicrobial resveratrol tetramers from the stem bark of Vatica oblongifoliassp. oblongifolia.}, author={Joanna R Zgoda-Pols and Alan J. Freyer and L. B. Killmer and John R Porter}, journal={Journal of natural products}, year={2002}, volume={65 11}, pages={ 1554-9 } }
Two new resveratrol tetramers, hopeaphenol A (1) and isohopeaphenol A (2), along with the known vaticaphenol A (3), were isolated from the stem bark of Vatica oblongifolia ssp. oblongifolia through bioassay-guided fractionation. The structures and their relative stereochemistry were determined by spectroscopic techniques. Compounds 1 and 3 demonstrated moderate activity against methicillin-resistant Staphylococcus aureus and Mycobacterium smegmatis.
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