Antimicrobial reactive oxygen and nitrogen species: concepts and controversies

@article{Fang2004AntimicrobialRO,
  title={Antimicrobial reactive oxygen and nitrogen species: concepts and controversies},
  author={Ferric C. Fang},
  journal={Nature Reviews Microbiology},
  year={2004},
  volume={2},
  pages={820-832}
}
  • F. Fang
  • Published 2004
  • Biology, Medicine
  • Nature Reviews Microbiology
Phagocyte-derived reactive oxygen and nitrogen species are of crucial importance for host resistance to microbial pathogens. Decades of research have provided a detailed understanding of the regulation, generation and actions of these molecular mediators, as well as their roles in resisting infection. However, differences of opinion remain with regard to their host specificity, cell biology, sources and interactions with one another or with myeloperoxidase and granule proteases. More than a… Expand
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