Antimicrobial properties of hemoglobin.

  title={Antimicrobial properties of hemoglobin.},
  author={Preethi Sheshadri and Jayanthi Abraham},
  journal={Immunopharmacology and immunotoxicology},
  volume={34 6},
Hemoglobin consists of a heme containing component and a globin unit. It exists as a tetramer with 2 α subunits and 2 β subunits in adults and with 2 α subunits and 2 γ chains in infants. On proteolytic cleavage, hemoglobin breaks down to produce many biologically active compounds, among which are hemocidins, those which exhibit antimicrobial property. The generation of these peptides does not depend on the blood group, Rhesus factor, age and sex of the healthy donors. The microbicidal activity… CONTINUE READING