Antimicrobial peptides in the stomach of Xenopus laevis.

  title={Antimicrobial peptides in the stomach of Xenopus laevis.},
  author={Kristin S. Moore and Charles L. Bevins and M M Brasseur and Natale Tomassini and Kristi Turner and Hubert Eck and Michael A. Zasloff},
  journal={The Journal of biological chemistry},
  volume={266 29},
Antimicrobial peptides are widely distributed in nature and appear to play a role in the host defense of plants and animals. In this study we report the existence of antimicrobial peptides in the stomach of the vertebrate Xenopus laevis, an animal previously shown to store high concentrations of antimicrobial peptides in its skin. Antimicrobial activity was detected in extracts of X. laevis stomach tissue and nine antimicrobial peptides were then purified. A novel 24-amino acid peptide… CONTINUE READING