Antimicrobial peptides derived from hemoglobin are expressed in epithelium of channel catfish (Ictalurus punctatus, Rafinesque).

@article{Ullal2008AntimicrobialPD,
  title={Antimicrobial peptides derived from hemoglobin are expressed in epithelium of channel catfish (Ictalurus punctatus, Rafinesque).},
  author={Anirudh J. Ullal and R Wayne Litaker and Edward J. Noga},
  journal={Developmental and comparative immunology},
  year={2008},
  volume={32 11},
  pages={
          1301-12
        }
}
The beta-chain of the respiratory protein hemoglobin (Hbbeta), has recently been identified in novel sites, including mammalian macrophages and alveolar epithelium, as well as in gill microsomes of fish. However, the functional significance of extra-erythrocytically expressed hemoglobin has been unclear. Here we show inducible expression and upregulation of antimicrobial peptides (AMPs) homologous to Hbbeta in the gill epithelium of channel catfish (Ictalurus punctatus) in response to parasitic… CONTINUE READING

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