Antimicrobial peptides are expressed and produced in healthy and inflamed human synovial membranes.

@article{Paulsen2002AntimicrobialPA,
  title={Antimicrobial peptides are expressed and produced in healthy and inflamed human synovial membranes.},
  author={Friedrich Paulsen and Thomas Pufe and Lenard Conradi and Deike J. Varoga and Michael Tsokos and Jann Papendieck and W. P. Petersen},
  journal={The Journal of pathology},
  year={2002},
  volume={198 3},
  pages={369-77}
}
The objective of this study was to determine the expression and production of antimicrobial peptides by healthy and inflamed human synovial membranes. Deposition of the antimicrobial peptides lysozyme, lactoferrin, secretory phospholipase A(2) (sPA(2)), matrilysin (MMP7), human neutrophil alpha-defensins 1-3 (HNP 1-3), human beta-defensin 1 (HBD-1), and human beta-defensin 2 (HBD-2) was determined by immunohistochemistry. Expression of mRNA for the antimicrobial peptides bactericidal… CONTINUE READING
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