Antimicrobial peptides: the ancient arm of the human immune system.

  title={Antimicrobial peptides: the ancient arm of the human immune system.},
  author={Jochen Wiesner and Andreas Vilcinskas},
  volume={1 5},
The production of peptides and small proteins with microbicidal activity collectively called antimicrobial peptides (AMPs) is commonly considered to be a primitive mechanism of immunity and has been extensively studied in insects and other non-vertebrate organisms. In addition, a variety of AMPs present in amphibian skin secretion has been well characterised. There is now increasing evidence that AMPs play a crucial role in human immunity as well. Virtually all human tissues and cells typically… CONTINUE READING
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