Antimicrobial peptide resistance in Neisseria meningitidis.

  title={Antimicrobial peptide resistance in Neisseria meningitidis.},
  author={Yih-ling Tzeng and David S. Stephens},
  journal={Biochimica et biophysica acta},
  volume={1848 11 Pt B},
Antimicrobial peptides (AMPs) play an important role as a host defense against microbial pathogens and are key components of the human innate immune response. Neisseria meningitidis frequently colonizes the human nasopharynx as a commensal but also is a worldwide cause of epidemic meningitis and rapidly fatal sepsis. In the human respiratory tract, the only known reservoir of N. meningitidis, meningococci are exposed to human endogenous AMPs. Thus, it is not surprising that meningococci have… CONTINUE READING

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