• Corpus ID: 39719974

Antimicrobial natural products from Plectranthus plants

@inproceedings{Rijo2013AntimicrobialNP,
  title={Antimicrobial natural products from Plectranthus plants},
  author={Patr{\'i}cia Rijo and Maria F{\'a}tima Sim{\~o}es and Gama Pinto},
  year={2013}
}
P. Rijo*, C.Faustino and M. Fatima Simoes iMed.UL Research Institute for Medicines and Pharmaceutical Sciences, Faculdade de Farmacia, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal CBios Research Centre for Health Sciences & Technologies (Pharmacology and Therapeutics Lab), Universidade Lusofona de Humanidades e Tecnologias, Campo Grande 376, 1749-024 Lisboa, Portugal 
No Paper Link Available
17 Citations
Highly Influential Citations
1
Background Citations
7
Methods Citations
1
Results Citations
1

Figures and Tables from this paper

17 Citations

Plectranthus ecklonii Benth: A Comprehensive Review Into its Phytochemistry and Exerted Biological Activities
TLDR
The widespread ethnobotanical and traditional uses of P. ecklonii can be scientifically justified by a range of biological activities, demonstrated by isolated secondary metabolites, which showcase the potential of this species in the development of economically important active pharmaceutical ingredients, particularly in anticancer therapy.
Parvifloron D from Plectranthus strigosus: Cytotoxicity Screening of Plectranthus spp. Extracts
TLDR
This study provides valuable information on the use of the Plectranthus genus as a source of bioactive compounds, namely P. strigosus acetonic extract showed the strongest antimicrobial and cytotoxic potential that could be explained by the presence of parvifloron D, a highly cytot toxic diterpene.
Unravelling new ethnopharmacological roles of Plectranthus species: biological activity screening
TLDR
The antielastase assay revealed that the organic extracts of P. grandidentatus (ethyl acetate 42.84 ± 4.2%) and neochilus (acetone 38.23 ± 1.8%) were the most active, while the non-cytotoxic compounds revealed unable to reduce NO production, after LPS stimulated inflammation.
Antimicrobial screening of Plectranthus madagascariensis and P. neochilus extracts
TLDR
In this work, aqueous, acetonic and methanolic extracts of P. madagascariensis and P. neochilus were prepared using several extraction methods and it was shown that the more polar compounds were the responsible for the antimicrobial activity.
Comparison Study of Different Extracts of Plectranthus madagascariensis, P. neochilus and the Rare P. porcatus (Lamiaceae): Chemical Characterization, Antioxidant, Antimicrobial and Cytotoxic Activities
TLDR
Medicinal plants of the Plectranthus genus (Lamiaceae) are known for their ethnopharmacological relevance, mainly against infectious, dermatologic and gastrointestinal pathologies, validating the traditional uses of such plants as anti-infectious agents.
Antimicrobial Activity of the Ethanolic and Aqueous Extract of Vicia faba L. (Fabaceae) at Three Different Concentrations in the Absence and Presence of Zn(OAc)2.2H2O
The aqueous and ethanolic extract of Passiflora edulis and Vicia faba L. (Fabaceae) exhibited antimicrobial activity against the pathogenic microorganisms: E. coli, S. aureus, K. pneumoniae and C.…
Reactivity study and biological activity of diterpenes from Plectranthus spp.
Nature is an attractive source of new therapeutic candidate compounds. The isolation of new natural products can provide novel scaffolds with potential biological activities, which may trigger the…
Screening the dermatological potential of Plectranthus species components: antioxidant and inhibitory capacities over elastase, collagenase and tyrosinase
TLDR
Overall, the experimental results showed the powerful antioxidant and inhibitory action on skin-related enzymes tyrosinase, collagenase and elastase of Plectranthus spp.
Antimicrobial abietane diterpenoids against resistant bacteria and biofilms
TLDR
Structural-activity relationship analysis suggests that the antimicrobial activity of abietane diterpenoids is related to some characteristic features of the abietan skeleton and is dependent on the degree of substitution, the nature and position of the substituents, and the overall lipophilicity of the compound.
ANTIMICROBIAL ACTIVITY OF THE ETHANOLIC AND AQUEOUS EXTRACT OF PASSION FRUIT (PASSIFLORA EDULIS SIMS), IN THE ABSENCE AND PRESENCE OF Zn(OAc)2.2H2O.
TLDR
Interestingly, there seems to be an increase in antimicrobial activity of the aqueous solution of the white ethanolic isolate in the presence of Zn (OAc).2H2O salt against pathogens in some cases and a decrease in another instance.
...
...

References

SHOWING 1-10 OF 72 REFERENCES
Antimicrobial Diterpenes from Salvia reptans
The roots of Salvia reptans Jacq. (Labiatae) yielded 8a 9a-epoxy-7-ketoroyleanone 1 and horminone 2 as the major antimicrobial agents. These isolates were found to be active against Bacillus cereus,…
Abietane acids: sources, biological activities, and therapeutic uses.
TLDR
Antimicrobial, antiulcer, and cardiovascular activities are the most representative for this class of diterpenoids, while others like allergenic, antiallergic, filmogenic, surfactant, antifeedant, etc. activities are also reported.
Structure and antimicrobial activity of diterpenes from the roots of Plectranthus hereroensis.
TLDR
Two abietane-type diterpenoids have been isolated from the roots of Plectranthus hereroensis (Labiatae) and showed antimicrobial activity against Staphylococcus aureus, Vibrio cholerae, Candida albicans, and Pseudomonas aeruginosa.
Antimicrobial study of the resinous exudates and of diterpenoids and flavonoids isolated from some Chilean Pseudognaphalium (Asteraceae).
Antiplasmodial activities of some abietane diterpenes from the leaves of five Plectranthus species.
TLDR
Overall, the cytotoxicity profile indicated a low degree of specificity towards the malaria parasite, and when combined with quinine, three compounds interacted in an additive manner whereas one interacted synergistically.
Abietanes from Plectranthus grandidentatus and P. hereroensis against methicillin- and vancomycin-resistant bacteria.
Plant Products as Antimicrobial Agents
TLDR
The current status of botanical screening efforts, as well as in vivo studies of their effectiveness and toxicity, are summarized and the structure and antimicrobial properties of phytochemicals are addressed.
Antimicrobial activity of diterpene resin acid derivatives.
Structure—antimicrobial activity relationships of abietane diterpenes from Salvia species
Antibacterial and anti-inflammatory activities of some plants used for medicinal purposes in Kenya.
...
...