Antimicrobial functions of mononuclear phagocytes.

  title={Antimicrobial functions of mononuclear phagocytes.},
  author={Jan A. M. Langermans and Wouter L. W. Hazenbos and Ralph van Furth},
  journal={Journal of immunological methods},
  volume={174 1-2},
One of the major functions of mononuclear phagocytes, i.e., monocytes and macrophages, is the phagocytosis and killing of microorganisms. To obtain more insight into the pathogenesis of infectious diseases and to develop new therapies against these diseases, a better understanding of the antimicrobial mechanisms employed by mononuclear phagocytes is essential. The present review gives a short description of the mononuclear phagocyte system and summarizes various methods that are used to study… CONTINUE READING