Antimicrobial effects of terpinen-4-ol against oral pathogens and its capacity for the modulation of gene expression.

@article{Bordini2018AntimicrobialEO,
  title={Antimicrobial effects of terpinen-4-ol against oral pathogens and its capacity for the modulation of gene expression.},
  author={Ester Alves Ferreira Bordini and Caroline Coradi Tonon and Renata Serignoli Francisconi and Fernando Augusto Cintra Magalh{\~a}es and Patricia Milagros Maquera-Huacho and Telma Blanca Lombardo Bedran and Sebasti{\~a}o Pratavieira and Lu{\'i}s Carlos Spolid{\'o}rio and Denise Madalena Palomari Spolidorio},
  journal={Biofouling},
  year={2018},
  pages={
          1-11
        }
}
This study evaluated the antibacterial activity of terpinen-4-ol against Streptococcus mutans and Lactobacillus acidophilus and its influence on gbpA (S. mutans) and slpA (L. acidophilus) gene expression. As measured by XTT assay, the concentrations of terpinen-4-ol that effectively inhibited the biofilm were 0.24% and 0.95% for S. mutans and L. acidophilus, respectively. Confocal microscopy revealed the presence of a biofilm attached to the enamel and dentin block surfaces with significant… CONTINUE READING
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