Antimicrobial defense and persistent infection in insects.

  title={Antimicrobial defense and persistent infection in insects.},
  author={Eleanor R. Haine and Yannick Moret and Michael T. Siva-Jothy and Jens Rolff},
  volume={322 5905},
During 400 million years of existence, insects have rarely succumbed to the evolution of microbial resistance against their potent antimicrobial immune defenses. We found that microbial clearance after infection is extremely fast and that induced antimicrobial activity starts to increase only when most of the bacteria (99.5%) have been removed. Our experiments showed that those bacteria that survived exposure to the insect's constitutive immune response were subsequently more resistant to it… CONTINUE READING
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