Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis

@inproceedings{Aldunate2015AntimicrobialAI,
  title={Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis},
  author={Muriel Aldunate and Daniela Srbinovski and Anna C. Hearps and Catherine F. Latham and Paul A. Ramsland and Raffi Gugasyan and Richard A. Cone and Gilda Tachedjian},
  booktitle={Front. Physiol.},
  year={2015}
}
Lactic acid and short chain fatty acids (SCFAs) produced by vaginal microbiota have reported antimicrobial and immune modulatory activities indicating their potential as biomarkers of disease and/or disease susceptibility. In asymptomatic women of reproductive-age the vaginal microbiota is comprised of lactic acid-producing bacteria that are primarily responsible for the production of lactic acid present at ~110 mM and acidifying the vaginal milieu to pH ~3.5. In contrast, bacterial vaginosis… CONTINUE READING
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