Antimicrobial and chemoattractant activity, lipopolysaccharide neutralization, cytotoxicity, and inhibition by serum of analogs of human cathelicidin LL-37.

@article{Ciornei2005AntimicrobialAC,
  title={Antimicrobial and chemoattractant activity, lipopolysaccharide neutralization, cytotoxicity, and inhibition by serum of analogs of human cathelicidin LL-37.},
  author={Cristina D Ciornei and Thorgerdur Sigurdard{\'o}ttir and Artur Schmidtchen and Mikael Bodelsson},
  journal={Antimicrobial agents and chemotherapy},
  year={2005},
  volume={49 7},
  pages={2845-50}
}
Antimicrobial peptides have been evaluated in vitro and in vivo as alternatives to conventional antibiotics. Apart from being antimicrobial, the native human cathelicidin-derived peptide LL-37 (amino acids [aa] 104 to 140 of the human cathelicidin antimicrobial peptide) also binds and neutralizes bacterial lipopolysaccharide (LPS) and might therefore have… CONTINUE READING