Antimicrobial and Cytotoxic Assessment of Marine Cyanobacteria - Synechocystis and Synechococcus

@article{Martins2008AntimicrobialAC,
  title={Antimicrobial and Cytotoxic Assessment of Marine Cyanobacteria - Synechocystis and Synechococcus},
  author={Ros{\'a}rio F. Martins and M{\'a}rio Ramos and Lars Herfindal and Jos{\'e} Albuquerque e Sousa and K. Sk{\ae}rven and Vitor Vasconcelos},
  journal={Marine Drugs},
  year={2008},
  volume={6},
  pages={1 - 11}
}
Aqueous extracts and organic solvent extracts of isolated marine cyanobacteria strains were tested for antimicrobial activity against a fungus, Gram-positive and Gram-negative bacteria and for cytotoxic activity against primary rat hepatocytes and HL-60 cells. Antimicrobial activity was based on the agar diffusion assay. Cytotoxic activity was measured by apoptotic cell death scored by cell surface evaluation and nuclear morphology. A high percentage of apoptotic cells were observed for HL-60… CONTINUE READING