Antimicrobial activity of two bactenecins against spirochetes.


Bac5 and Bac7 are antimicrobial peptides of bovine neutrophils that act on enteric gram-negative bacteria. We report here that these two peptides immobilize and kill Leptospira interrogans and Leptospira biflexa with MBCs of 6 to 25 micrograms/ml. Conversely, although both peptides bind to Borrelia burgdorferi, the organism is resistant to their action.

Cite this paper

@article{Scocchi1993AntimicrobialAO, title={Antimicrobial activity of two bactenecins against spirochetes.}, author={Marco Scocchi and Domenico Romeo and Marina Cinco}, journal={Infection and immunity}, year={1993}, volume={61 7}, pages={3081-3} }