Antimicrobial activity of the recombinant designer host defence peptide P-novispirin G10 in infected full-thickness wounds of porcine skin.

@article{Jacobsen2007AntimicrobialAO,
  title={Antimicrobial activity of the recombinant designer host defence peptide P-novispirin G10 in infected full-thickness wounds of porcine skin.},
  author={Frank Jacobsen and Ali Mohammadi-Tabrisi and Tobias Hirsch and Dominik Mittler and Per Holse Mygind and Carsten Sonksen and Dora Raventos and H. H. Kristensen and Soren Gatermann and Marcus Lehnhardt and Adrien Daigeler and Hans Ulrich Steinau and Lars Steinstraesser},
  journal={The Journal of antimicrobial chemotherapy},
  year={2007},
  volume={59 3},
  pages={493-8}
}
OBJECTIVES The growing number of patients with impaired wound healing and the development of multidrug-resistant bacteria demand the investigation of alternatives in wound care. The antimicrobial activity of naturally occurring host defence peptides and their derivatives could be one alternative to the existing therapy options for topical treatment of wound infection. Therefore, the aim of this study was to investigate the antimicrobial activity of proline-novispirin G10 (P-novispirin G10) in… CONTINUE READING

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