Antimicrobial activity of the bufadienolides marinobufagin and telocinobufagin isolated as major components from skin secretion of the toad Bufo rubescens.

@article{Filho2005AntimicrobialAO,
  title={Antimicrobial activity of the bufadienolides marinobufagin and telocinobufagin isolated as major components from skin secretion of the toad Bufo rubescens.},
  author={Geraldino A Cunha Filho and C. A. Schwartz and I. S. Resck and M. M. Murta and S. S. Lemos and M. S. Castro and C. Kyaw and O. R. Pires and J. Leite and C. Bloch and E. F. Schwartz},
  journal={Toxicon : official journal of the International Society on Toxinology},
  year={2005},
  volume={45 6},
  pages={
          777-82
        }
}
The increase in the emergence of antibiotic-resistant microorganisms and difficult to treat infections caused by these pathogens stimulate research aiming the identification of novel antimicrobials. Skin secretion of amphibian contains a large number of biologically active compounds, including compounds that performance defense mechanisms against microorganisms. In the present work, two antimicrobial bufadienolides, telocinobufagin (402.1609 Da) and marinobufagin (400.1515 Da), were isolated… Expand
Antibacterial, modulatory activity of antibiotics and toxicity from Rhinella jimi (Stevaux, 2002) (Anura: Bufonidae) glandular secretions.
Identification of Bufadienolides from the Boreal Toad, Anaxyrus boreas, Active Against a Fungal Pathogen
Antileishmanial and antitrypanosomal activity of bufadienolides isolated from the toad Rhinella jimi parotoid macrogland secretion.
Biological activities of leaf extracts from selected Kalanchoe species and their relationship with bufadienolides content
Antibacterial activity of Helleborus bocconei Ten. subsp. siculus root extracts.
Antiproliferative activity of Rhinella marina and Rhaebo guttatus venom extracts from Southern Amazon.
Biological activities of skin and parotoid gland secretions of bufonid toads (Bufo bufo, Bufo verrucosissimus and Bufotes variabilis) from Turkey.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 30 REFERENCES
Structures of novel bufadienolides in the eggs of a toad, Bufo marinus.
Antibacterial activity of lactose-binding lectins from Bufo arenarum skin.
A novel antimicrobial peptide from Bufo bufo gargarizans.
Studies on cardiotonic steroids from the skin of Japanese toad.
Indirect cardiotoxic activity of the caecilian Siphonops paulensis (Gymnophiona, Amphibia) skin secretion.
Antimicrobial peptides from amphibian skin: what do they tell us?
Mechanism of action of the antimicrobial peptide buforin II: buforin II kills microorganisms by penetrating the cell membrane and inhibiting cellular functions.
Antimicrobial peptides from ranid frogs: taxonomic and phylogenetic markers and a potential source of new therapeutic agents.
...
1
2
3
...