Antimicrobial activity of CHIR-090, an inhibitor of lipopolysaccharide biosynthesis, against the Burkholderia cepacia complex.

Abstract

A striking characteristic of cystic fibrosis (CF) is susceptibility to life-limiting bacterial infections of the respiratory tract (13, 26). Members of the Burkholderia cepacia complex are a particular cause of anxiety to CF individuals (8, 14, 23) since they display high resistance to antibiotics and biocides (3, 32), possibly linked to their relatively… (More)
DOI: 10.1128/AAC.01600-09

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@article{Bodewits2010AntimicrobialAO, title={Antimicrobial activity of CHIR-090, an inhibitor of lipopolysaccharide biosynthesis, against the Burkholderia cepacia complex.}, author={Karin Bodewits and Christian R. H. Raetz and John R W Govan and Dominic J. Campopiano}, journal={Antimicrobial agents and chemotherapy}, year={2010}, volume={54 8}, pages={3531-3} }