Antimicrobial activity and spectrum of PPI-0903M (T-91825), a novel cephalosporin, tested against a worldwide collection of clinical strains.

@article{Sader2005AntimicrobialAA,
  title={Antimicrobial activity and spectrum of PPI-0903M (T-91825), a novel cephalosporin, tested against a worldwide collection of clinical strains.},
  author={H{\'e}lio S. Sader and Thomas R. Fritsche and Kon{\'e} Kaniga and Yigong Ge and Ronald N. Jones},
  journal={Antimicrobial agents and chemotherapy},
  year={2005},
  volume={49 8},
  pages={3501-12}
}
PPI-0903M is a novel N-phosphono-type cephalosporin active against oxacillin-resistant staphylococci and many other gram-positive organisms. This study evaluated the in vitro activity and spectrum of PPI-0903M against 1,478 recent clinical isolates collected from 80 medical centers (22 countries). PPI-0903M demonstrated broader in vitro activity against gram-positive bacteria, particularly against multidrug-resistant staphylococci and streptococci of current clinical concern, than currently… CONTINUE READING

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